What causes steroid cataracts? A review of steroid‐induced posterior subcapsular cataracts
نویسندگان
چکیده
منابع مشابه
Refractive error changes in cortical, nuclear, and posterior subcapsular cataracts.
AIMS To determine the effect of the three main morphological types of cataract on refractive error. METHODS Data were prospectively collected from 77 subjects (age 67 (SD 8) years) with one morphological type of cataract. 34 had cortical, 21 had nuclear, and 21 had posterior subcapsular cataract. 22 subjects with clear lenses (60 (7) years) were recruited as controls. The spherical equivalent...
متن کاملMatrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts
PURPOSE To evaluate the level of matrix metalloproteinase (MMP)-2 and MMP-9 activities in patients with steroid induced posterior subcapsular cataract (PSC). METHODS This prospective, observational study comprised of 156 patients having either steroid induced PSC (n=50) or non-steroidal PSC (n=106) were performed to evaluate the level of MMP-2 and MMP-9 activities in the lens epithelial cells...
متن کاملRefractive changes in nuclear, cortical and posterior subcapsular cataracts. effect of the type and grade.
PURPOSE To determine the effect of main morphological types and grades of age-related cataracts on refractive error. METHODS We measured 276 subjects with optical compensation prior to the development of cataract. We evaluated 224 eyes with nuclear cataract, 125 with cortical cataract, and 103 with posterior subcapsular (PSC) cataract classified with LOCSIII. We measured visual acuity (VA) wi...
متن کاملLens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts.
Transgenic mice were generated by microinjection of a construct containing a self-activating human TGF-beta1 cDNA driven by the lens-specific alphaA-crystallin promoter. Seven transgenic founder mice were generated, and four transgenic lines expressing TGF-beta1 were characterized. By postnatal day 21, mice from the four families exhibited anterior subcapsular cataracts. The lenses in these mic...
متن کاملSCIENTIFIC REPORT Refractive error changes in cortical, nuclear, and posterior subcapsular cataracts
Aims: To determine the effect of the three main morphological types of cataract on refractive error. Methods: Data were prospectively collected from 77 subjects (age 67 (SD 8) years) with one morphological type of cataract. 34 had cortical, 21 had nuclear, and 21 had posterior subcapsular cataract. 22 subjects with clear lenses (60 (7) years) were recruited as controls. The spherical equivalent...
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ژورنال
عنوان ژورنال: Clinical and Experimental Optometry
سال: 2002
ISSN: 0816-4622,1444-0938
DOI: 10.1111/j.1444-0938.2002.tb03011.x